Nutrisystem D

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Offer Terms and Conditions

†Fast 5+ and free shakes with any 28-day program, first order only.

**Lock in 2014 prices and free shipping (Continental US only) with 28-day auto-delivery program purchase only. Price lock valid on each consecutive 28-day auto-delivery order while on program. With this offer you receive an additional discount off the Full Retail Value with each consecutive 28-day auto-delivery order as long as you are on program. With Auto-Delivery, you are automatically charged and shipped your 28-Day program once every 4 weeks unless you cancel. You can cancel Auto-Delivery at any time by calling 1-800-727-8046. If you cancel prior to paying for your second consecutive 28-Day program delivery, your payment method will be charged for Continental U.S. shipping and the amount of any auto-delivery discount received on your first 28-Day program delivery. For all 28-day orders, your payment method will be charged a $19.99 shipping fee (1) if you cancel after your order has been processed; and (2) if you refuse the order at time of delivery. The Nutrisystem Select program is available to Continental US residents only and cannot be shipped to PO Boxes, APO Boxes or military addresses. Cannot be combined with any prior or current discount or offer. Limit one offer per customer.

If you're not 100% satisfied, call to cancel within 14 days and return remaining non-frozen food to us for a full refund, less shipping. Guarantee good on new 28-Day plans, first order only. Limit one Guarantee per customer.

Request for your free Patient Education Kit Close

With our unique direct-to-consumer platform, we are able to provide a comprehensive weight loss solution for your patients to complement their experiences in your office. There is no need for you to carry inventory, as we ship the program directly to customers' doors and provide a support system over the phone.

The kit contains program materials you can provide to your patients, including a special offer for Nutrisystem® D™.

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Clinical Research

The scientific literature supports key components of the programs, including the use of pre-packaged meals, low-GI foods, remote counseling, and self-monitoring of eating, activity, and progress. In addition to the broad scientific support for elements of the Nutrisystem programs, there is direct evidence in support of the Nutrisystem programs from clinical trials as well as analyses of our customers' outcomes.

Clinical Trials

1. Foster GD et al. The effects of a commercially available weight loss program among obese patients with type 2 diabetes: a randomized study. Postgraduate medicine 2009; 121:113-18.
Click here to view abstract

2. Foster GD et al. A randomized comparison of a commercially available portion-controlled weight-loss intervention with a diabetes self-management education program. Nutrition and Diabetes 2013; 3:e63. : 10.1038/nutd.2013.3.
Click here to view abstract

These two clinical trials examined the effects of D® on weight, hemoglobin A1C, and several additional metabolic outcomes among participants with type 2 diabetes. The 2009 study compared 3 months of Nutrisystem D, in conjunction with counseling sessions, to 3 months of information and support sessions about diabetes management. In months 4-6, all participants received Nutrisystem D. Patients on insulin were excluded from this study. The 2013 study, which included participants on insulin, compared Nutrisystem D, in conjunction with counseling sessions, to structured diabetes self-management education. Both interventions were delivered in 9 sessions over 6 months.

The table below summarizes the mean 6-month changes from baseline among all participants randomized to receive the Nutrisystem D intervention in both trials, separately and combined. These data are from an unpublished secondary analysis of within-group changes observed in the intent-to-treat samples of the two trials. All changes from baseline reported here are statistically significant (p < 0.05).

Change Variable

Study 1
(n=35)

Study 2
(n=50)

Combined
(n = 85)

Weight (% change in initial weight)

- 7.1%

- 7.8%

- 7.5%

Body Mass Index

- 3.1 kg/m2

- 3.5% kg/m2

- 3.3 kg/m2

Waist Circumference

- 3.2 in

- 2.5 in

- 2.8 in

A1c

- 0.8%

- 0.7%

- 0.73%

Total Cholesterol

- 14.2 mg/dl

- 8.6 mg/dl

- 10.9 mg/dl

Triglycerides

- 44 mg/dl

- 26.3 mg/dl

- 33.6 mg/dl

As shown in the figure below, more than half of Nutrisystem D participants in the two studies combined achieved clinically meaningful changes in weight and A1C. Among persons who entered the study with A1C > 7.0%, more than half achieved A1C < 7.0% at 6 months.

Percentage of Participants

These findings suggest both statistically and clinically meaningful reductions in body weight and A1C among participants who received the Nutrisystem D intervention, along with counseling. As detailed below, the weight losses observed in the clinical trials are corroborated by real-world customer results.

3. Fabricatore AN et al. Reduction in glycemic variability and hyperglycemia with a low-glycemic index portion-controlled diet in persons with type 2 diabetes. Presented at the 72nd Annual Scientific Sessions of the American Diabetes Association. Philadelphia, PA June 10, 2012. 
Click here to view abstract.

This randomized cross-over trial employed continuous glucose monitoring (CGM) to assess multiple indicators of glycemic variability and stability in obese adults with type 2 diabetes. Subjects served as their own controls, consuming their usual diet and Nutrisystem D, in random order, for two weeks each, separated by a one-week washout period. During consumption of Nutrisystem D, participants had significantly lower average blood glucose (137.2 vs. 148.9 mg/dl, p < 0.01) and significantly less glycemic variability, as measured by standard deviation (31.8 vs. 36.1 mg/dl, p < 0.04) and interquartile range (38.9 vs. 45.0 mg/dl, p < 0.05) of blood glucose values. Additionally, participants recorded significantly fewer values in the hyperglycemic range (i.e., > 180 mg/dl; 13.4% vs. 21.0% of values, p < 0.03) without a significant increase in hypoglycemic values (i.e., < 70 mg/dl; 3.3% vs. 1.3%, p = 0.19).  The figure below shows subjects' average blood glucose tracings during consumption of the portion-controlled diet (i.e., Nutrisystem D) versus their usual diet.

Blood Glucose

Customer Studies

1. Daggy BP et al. Trial participants and paying customers achieved similar weight losses with a commercial weight loss program for type 2 diabetes. Diabetes 2011; 60 (Suppl. 1); A702.
Click here to view abstract.

Nutrisystem researchers attempted to determine whether the results of the Foster et al. (2009) clinical trial were representative of the outcomes achieved by actual Nutrisystem D customers who were not participating in a structured trial. Nutrisystem D customers who used Nutrisystem's online weight-tracking tool to record their weight at baseline (i.e., time of initial purchase) and three months later (i.e., to match the length of the intervention in the clinical trial) were included in the analysis. The sample of 5,588 customers (64% women, mean age = 52.5 y, mean weight = 107.5 kg, mean BMI = 37.6 kg/m2) achieved an average 3-month weight loss of 8.2 kg, which represented a 7.6% reduction in initial body weight. By comparison, participants in the Foster et al. trial also lost 8.2 kg, representing a 7.1% weight loss. Approximately two-thirds of trial participants (67.7%) lost at least 5% of their initial weight, compared with over three-quarters (78.4%) of customers who reached that target. Thus, it appears that actual Nutrisystem D customers achieved similar weight losses to those achieved in a clinical trial.

2. Fabricatore AN et al. Results not typical? Subjective and objective success in a commercial weight loss program.Presented at the Annual Scientific Meeting ofThe Obesity Society. Orlando, FL. October 2, 2011.
Click here to view abstract.

Advertisements and testimonials for commercial weight loss programs (including Nutrisystem) often depict dramatic results that must be disclaimed as "not typical." This study attempted to define the typical results achieved by Nutrisystem customers. The only criterion for inclusion in the analysis was that the customer recorded their weight at baseline and at 3 months, which yielded a sample of 103,693 customers (70% women, mean age 46.9 y, mean weight = 216.4 lb, mean BMI = 34.3 kg/m2). The average weight loss at 3 months was 18.2 lb, representing an 8.3% reduction in initial weight. Although few customers (4.5%) reached their self-selected weight loss goal (mean goal = 54 lb loss) at 3 months, nearly four-fifths (79.4%) achieved at least a 5% weight loss in 3 months, including 33% of customers who lost 10% or more of their starting weight. This analysis suggested that the typical result for Nutrisystem customers who maintained some level of engagement for 3 months was a clinically meaningful weight loss.

3. Daggy BP et al. Holiday weight change in a commercial weight loss program. Presented at Advances and Controversies in Clinical Nutrition (a meeting of the American Society for Nutrition). San Francisco, CA. February 26, 2011.
Click here to view abstract.

The period spanning Thanksgiving to New Year's Day is a particularly difficult time for weight control. Nutrisystem researchers sought to examine how program customers fared during that time. Customers who recorded their weight in the week before Thanksgiving and again in the week following New Year's Day were included in the analysis. The average weight loss achieved during that 6-week period was 5.5 lb. For comparison purposes, weight changes during similar 6-week periods (beginning 3, 6, and 9 months prior to Thanksgiving) were examined and found to range from 8.4 to 9.5 lb. Thus, although customers lost less weight during the holiday season than during other times of the year, the average result was a loss of nearly 1 lb. per week during that traditionally difficult period for weight control.

Nutrisystem Supports Clinical Research

Nutrisystem is proud to partner with a number of academic institutions to support clinical investigations that include products and programs. Support mechanisms include investigator-initiated grants, in-kind product donations, and access to de-identified data. Please direct all inquiries to research@nutrisystem.com.

Nutrisystem D News & Information Center
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a national strategic partner of - American Diabetes Association(R)

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